Luke Hendrie, who has been sidelined with a hamstring injury since limping off at Cambridge last month, will again miss out on Tuesday night.
Ludvig Öhman (illness) and Max Wright (thigh) could both be set to return against The Robins.
Mattie Pollock is available again after serving a one-match suspension at the PTS Academy Stadium at the weekend.
Moses Ogbu made a welcome return from the bench on Saturday and could come into contention for a start in Anthony Limbrick's side.
Tuesday’s visitors are likely to be without the services of Sean Long, but Reuben Reid stepped up his recovery with more minutes during the 1-1 draw against Colchester United on Saturday afternoon.
Cheltenham have won two of their last six Sky Bet League Two fixtures, drawn three and lost by the odd goal against local rivals Forest Green Rovers.
Head to Head
The last six meetings between the two sides have produced just two victories for the Mariners. Perhaps the most memorable one was under Russell Slade in 2017 where goals from Siriki Debele and Danny Collins sealed a 3-2 victory at Whaddon Road.
FL-4 22/10/2016 H 0-1 4,809
FL-4 17/04/2017 A 1-2 3,550 Berrett
FL-4 17/10/2017 A 3-2 2,469 Dembele (2), Collins
FL-4 03/02/2018 H 1-1 3,352 Jackson
FL-4 08/12/2018 A 1-2 2,775 Embleton
FL-4 16/02/2019 H 1-0 4,940 Thomas
As usual, match updates will be provided by the club’s official twitter account (@OfficialGTFC). We will keep you up to date with the action to ensure you don’t miss a kick – delivering a match report shortly after the final whistle with post-match reaction from Town's caretaker boss, Anthony Limbrick.
Watch Live on iFollow Mariners
This game will be shown live on iFollow for overseas fans and supporters living in the UK. Matt Dean and former Town boss Alan Buckley will be on the comms.
Grimsby to win and BTTS is now 5/1 from 4/1 - with a Sky Bet Price Boost. more >>
Man in the Middle:
Suffolk based official Chris Pollard will take charge of his very first Town game on Tuesday night.
The 36-year-old was officiating on both the National League and the Premier League 2 competitions in 2018/19 but was promoted to the EFL list of referees during the summer.
Key Men for The Robins – Ryan Broom and veteran frontman Luke Varney already have 12 goals between them and pose a massive threat.
Broom was on target against the Mariners in last season's 2-1 defeat at the Jonny-Rocks Stadium. The Versatile midfielder has also provided four assists for the Robins so far.
“We need a win – 100 per cent. We haven’t had a win for a little while now.
“That’s what made the result on Saturday harder to take, because we had played some good football in the game, certainly in the first half.
“If we had got in front, that might have given us something to hold on to. Goals change games and we need a win, there’s no doubt about it.”
Speaking to their official website, Duff said: "We would have liked to have played them when the game was called off because we were in a really good run then and they were having a bit of a difficult time.
"It is what it is. It was unplayable - there was no doubt about it. We go up there still on a decent run and we've got to go and back ourselves. People keep talking about the games in hand and this is one of them so it's a big marker.
"I went to watch them last week at Newport and they fought and they scrapped for everything. There are no easy games and we won't be going there naive enough to think that we can just rock up anywhere.
"I say it all the time because I believe in it. We need to be a hundred per cent fully at it, committed, and use the ball well to win the game."