We get the 2017/18 Sky Bet League Two Season underway at Chesterfield on Saturday and Sky Bet have the Mariners as underdogs at the Proact Stadium.
Russell Slade's side are 9/4 to bag the three points, with the Spireites now at 6/5.
Predicting the time of the First Goal is always popular with Town fans.
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Or you might fancy a punt on the first goalscorer at The Proact Stadium.
Town striker Sam Jones is a good bet to bang in the first goal of the game at 6/1, with Scott Vernon at 9/1, Tom Bolarinwa at 11/1, and summer signing Siriki Dembele at 12/1.
What are the bookies saying about Town's promotion chances?
The Sky Bet EFL Team-by-team guide say: Russell Slade is back at Grimsby but I predict another mid-table finish for the Mariners in their second season back in the EFL.
Underdogs eh! Town are surely worth a cheeky little bet at 40/1 to be crowned champions in May?
Or a flutter on the Mighty Mariners being promoted to Sky Bet League One at 8/1?
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