Both players missed last week's trip to Barnet with hamstring injuries and could miss out against title chasing Argyle.
Gavin Gunning will serve the third game of his three match suspension on Saturday.
Russell Slade has confirmed that Akwasi Asante has undergone surgery on his troublesome ankle. Speaking at today's press conference, the Town boss said: "Asante has had an operation on an ankle that needed clearing out. There was a little foreign body in there that needed to be extracted. That will probably take a few months, probably the back end of pre season before he will be in doing at bit more work with us.
"He's had it done, that's the good thing, " he added.
Russell Slade also confirmed that Luke Maxwell has been allowed to return to his parent club Birmingham City.
Ashley Chambers is available to the Town boss after completing his loan at Nuneaton Town. The midfielder scored nine goals in fifteen games for the Warwickshire side.